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Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration
RATIONALE: Much evidence indicates that individuals use tobacco primarily to experience the psychopharmacological properties of nicotine. Varenicline, a partial α4β2 nicotinic acetylcholine receptor (nAChR) agonist, is effective in reducing nicotine craving and relapse in smokers, suggesting that α4...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033995/ https://ncbi.nlm.nih.gov/pubmed/20924754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-2024-3 |
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