Failure of Thymidine Kinase-Negative Herpes Simplex Virus To Reactivate from Latency following Efficient Establishment

Thymidine kinase-negative mutants of herpes simplex virus did not reactivate from latency in mouse trigeminal ganglia, even when their latent viral loads were comparable to those that permitted reactivation by wild-type virus. Thus, reduced establishment of latency does not suffice to account for th...

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הוצא לאור ב:	J Virol
Principais autores:	Chen, Shih-Heng, Pearson, Angela, Coen, Donald M., Chen, Shun-Hua
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2004
נושאים:	Pathogenesis and Immunity
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303395/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14671133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.1.520-523.2004
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