Specific inhibitors of herpes simplex virus thymidine kinase diminish reactivation of latent virus from explanted murine ganglia.

Two specific inhibitors of herpes simplex virus thymidine kinase, N2-phenyl-2'-deoxyguanosine and N2-(m-trifluoromethylphenyl)guanine, were tested for their ability to inhibit the reactivation of virus from explant cultures of latently infected murine trigeminal ganglia. Both compounds significantly...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Leib, D A, Ruffner, K L, Hildebrand, C, Schaffer, P A, Wright, G E, Coen, D M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168150/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.1285
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