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Specific inhibitors of herpes simplex virus thymidine kinase diminish reactivation of latent virus from explanted murine ganglia.

Two specific inhibitors of herpes simplex virus thymidine kinase, N2-phenyl-2'-deoxyguanosine and N2-(m-trifluoromethylphenyl)guanine, were tested for their ability to inhibit the reactivation of virus from explant cultures of latently infected murine trigeminal ganglia. Both compounds significantly...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Leib, D A, Ruffner, K L, Hildebrand, C, Schaffer, P A, Wright, G E, Coen, D M
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168150/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.1285
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