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Failure of Thymidine Kinase-Negative Herpes Simplex Virus To Reactivate from Latency following Efficient Establishment

Thymidine kinase-negative mutants of herpes simplex virus did not reactivate from latency in mouse trigeminal ganglia, even when their latent viral loads were comparable to those that permitted reactivation by wild-type virus. Thus, reduced establishment of latency does not suffice to account for th...

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Bibliografiske detaljer
Main Authors: Chen, Shih-Heng, Pearson, Angela, Coen, Donald M., Chen, Shun-Hua
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC303395/
https://ncbi.nlm.nih.gov/pubmed/14671133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.520-523.2004
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