Control of Heterologous Hepatitis C Virus Infection in Chimpanzees Is Associated with the Quality of Vaccine-Induced Peripheral T-Helper Immune Response

Prophylactic hepatitis C virus (HCV) vaccine trials with human volunteers are pending. There is an important need for immunological end points which correlate with vaccine efficacy and which do not involve invasive procedures, such as liver biopsies. By using a multicomponent DNA priming-protein boo...

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Autors principals: Rollier, C., Depla, E., Drexhage, J. A. R., Verschoor, E. J., Verstrepen, B. E., Fatmi, A., Brinster, C., Fournillier, A., Whelan, J. A., Whelan, M., Jacobs, D., Maertens, G., Inchauspé, G., Heeney, J. L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC303385/
https://ncbi.nlm.nih.gov/pubmed/14671100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.187-196.2004
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