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A Histone Deacetylase-Dependent Screen in Yeast

Histone deacetylase (HDAC) proteins are promising targets for cancer treatment, as shown by the recent FDA approval of the HDAC inhibitor suberoylanilide hydroxamic acid (SAHA, Vorinostat,) for the treatment of cutaneous T-cell lymphoma. To identify additional potent inhibitors and characterize HDAC...

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Dades bibliogràfiques
Autors principals: Weerasinghe, Sujith V. W., Wambua, Magdalene, Pflum, Mary Kay H.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033752/
https://ncbi.nlm.nih.gov/pubmed/20863708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.08.045
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