A Histone Deacetylase-Dependent Screen in Yeast

Histone deacetylase (HDAC) proteins are promising targets for cancer treatment, as shown by the recent FDA approval of the HDAC inhibitor suberoylanilide hydroxamic acid (SAHA, Vorinostat,) for the treatment of cutaneous T-cell lymphoma. To identify additional potent inhibitors and characterize HDAC...

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Hlavní autoři: Weerasinghe, Sujith V. W., Wambua, Magdalene, Pflum, Mary Kay H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033752/
https://ncbi.nlm.nih.gov/pubmed/20863708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.08.045
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