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A Histone Deacetylase-Dependent Screen in Yeast

Histone deacetylase (HDAC) proteins are promising targets for cancer treatment, as shown by the recent FDA approval of the HDAC inhibitor suberoylanilide hydroxamic acid (SAHA, Vorinostat,) for the treatment of cutaneous T-cell lymphoma. To identify additional potent inhibitors and characterize HDAC...

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Main Authors: Weerasinghe, Sujith V. W., Wambua, Magdalene, Pflum, Mary Kay H.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033752/
https://ncbi.nlm.nih.gov/pubmed/20863708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.08.045
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