Cytochrome P450 2J2 Is Highly Expressed in Hematologic Malignant Diseases and Promotes Tumor Cell Growth

Cytochrome P450 2J2 (CYP2J2) epoxygenase converts arachidonic acid to four regioisomeric epoxyeicosatrienoic acids (EETs) that exert multiple biological effects in the cardiovascular system and in various human solid cancers. However, it is unknown whether this enzyme is expressed or plays any role...

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Main Authors: Chen, Chen, Wei, Xin, Rao, Xiaoquan, Wu, Jun, Yang, Shenglan, Chen, Fuqiong, Ma, Ding, Zhou, Jianfeng, Dackor, Ryan T., Zeldin, Darryl C., Wang, Dao Wen
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Pharmacology and Experimental Therapeutics 2011
Ábhair:
Chemotherapy, Antibiotics, and Gene Therapy
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033713/
https://ncbi.nlm.nih.gov/pubmed/21030485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.174805
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