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Cytochrome P450 2J2 Is Highly Expressed in Hematologic Malignant Diseases and Promotes Tumor Cell Growth

Cytochrome P450 2J2 (CYP2J2) epoxygenase converts arachidonic acid to four regioisomeric epoxyeicosatrienoic acids (EETs) that exert multiple biological effects in the cardiovascular system and in various human solid cancers. However, it is unknown whether this enzyme is expressed or plays any role...

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Autors principals: Chen, Chen, Wei, Xin, Rao, Xiaoquan, Wu, Jun, Yang, Shenglan, Chen, Fuqiong, Ma, Ding, Zhou, Jianfeng, Dackor, Ryan T., Zeldin, Darryl C., Wang, Dao Wen
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033713/
https://ncbi.nlm.nih.gov/pubmed/21030485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.174805
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