Cytochrome P450 2J2 Is Highly Expressed in Hematologic Malignant Diseases and Promotes Tumor Cell Growth

Cytochrome P450 2J2 (CYP2J2) epoxygenase converts arachidonic acid to four regioisomeric epoxyeicosatrienoic acids (EETs) that exert multiple biological effects in the cardiovascular system and in various human solid cancers. However, it is unknown whether this enzyme is expressed or plays any role...

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Hlavní autoři: Chen, Chen, Wei, Xin, Rao, Xiaoquan, Wu, Jun, Yang, Shenglan, Chen, Fuqiong, Ma, Ding, Zhou, Jianfeng, Dackor, Ryan T., Zeldin, Darryl C., Wang, Dao Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2011
Témata:
Chemotherapy, Antibiotics, and Gene Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033713/
https://ncbi.nlm.nih.gov/pubmed/21030485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.174805
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