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Rapid emergence of protease inhibitor resistance in hepatitis C virus

Approximately 170 million people worldwide are infected with hepatitis C virus (HCV). Current standard therapy leads to sustained viral elimination in only about 50% of patients treated. Telaprevir, a novel HCV protease inhibitor, has demonstrated substantial antiviral activity in patients with chro...

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Bibliografische gegevens
Hoofdauteurs: Rong, Libin, Dahari, Harel, Ribeiro, Ruy M., Perelson, Alan S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033690/
https://ncbi.nlm.nih.gov/pubmed/20445200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000544
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