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Phosphodiesterases Catalyze Hydrolysis of cAMP-bound to Regulatory Subunit of Protein Kinase A and Mediate Signal Termination

Although extensive structural and biochemical studies have provided molecular insights into the mechanism of cAMP-dependent activation of protein kinase A (PKA), little is known about signal termination and the role of phosphodiesterases (PDEs) in regulatory feedback. In this study we describe a nov...

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Detaylı Bibliyografya
Asıl Yazarlar: Moorthy, Balakrishnan Shenbaga, Gao, Yunfeng, Anand, Ganesh S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033673/
https://ncbi.nlm.nih.gov/pubmed/20923972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.002295
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