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CD3/CD28 Costimulation-Induced NF-κB Activation Is Mediated by Recruitment of Protein Kinase C-θ, Bcl10, and IκB Kinase β to the Immunological Synapse through CARMA1

CARMA1 (also known as CARD11) is a scaffold molecule and contains a caspase-recruitment domain (CARD) and a membrane-associated guanylate kinase-like (MAGUK) domain. It plays an essential role in mediating CD3/CD28 costimulation-induced NF-κB activation. However, the molecular mechanism by which CAR...

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Dades bibliogràfiques
Publicat a:Mol Cell Biol
Autors principals: Wang, Donghai, Matsumoto, Reiko, You, Yun, Che, Tuanjie, Lin, Xue-Yan, Gaffen, Sarah L., Lin, Xin
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303359/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673152/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.164-171.2003
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