CD3/CD28 Costimulation-Induced NF-κB Activation Is Mediated by Recruitment of Protein Kinase C-θ, Bcl10, and IκB Kinase β to the Immunological Synapse through CARMA1

CARMA1 (also known as CARD11) is a scaffold molecule and contains a caspase-recruitment domain (CARD) and a membrane-associated guanylate kinase-like (MAGUK) domain. It plays an essential role in mediating CD3/CD28 costimulation-induced NF-κB activation. However, the molecular mechanism by which CAR...

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Hlavní autoři: Wang, Donghai, Matsumoto, Reiko, You, Yun, Che, Tuanjie, Lin, Xue-Yan, Gaffen, Sarah L., Lin, Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC303359/
https://ncbi.nlm.nih.gov/pubmed/14673152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.164-171.2003
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