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Activation of the Heterodimeric IκB Kinase α (IKKα)-IKKβ Complex Is Directional: IKKα Regulates IKKβ under Both Basal and Stimulated Conditions
Signal-induced nuclear expression of the eukaryotic NF-κB transcription factor involves the stimulatory action of select mitogen-activated protein kinase kinase kinases on the IκB kinases (IKKα and IKKβ) which reside in a macromolecular signaling complex termed the signalsome. While genetic studies...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC85235/ https://ncbi.nlm.nih.gov/pubmed/10648602 |
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