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Activation of the Heterodimeric IκB Kinase α (IKKα)-IKKβ Complex Is Directional: IKKα Regulates IKKβ under Both Basal and Stimulated Conditions

Signal-induced nuclear expression of the eukaryotic NF-κB transcription factor involves the stimulatory action of select mitogen-activated protein kinase kinase kinases on the IκB kinases (IKKα and IKKβ) which reside in a macromolecular signaling complex termed the signalsome. While genetic studies...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: O'Mahony, Alison, Lin, Xin, Geleziunas, Romas, Greene, Warner C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC85235/
https://ncbi.nlm.nih.gov/pubmed/10648602
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