Laddar...
Bioactivation of Anti-Tuberculosis Thioamide and Thiourea Prodrugs by Bacterial and Mammalian Flavin Monooxygenases
The thioamide and thiourea class of antituberculosis agents encompasses prodrugs that are oxidatively converted to their active forms by the flavin monooxygenase EtaA of Mycobacterium tuberculosis. Reactive intermediates produced in the EtaA-catalyzed transformations of ethionamide and prothionamide...
Sparad:
| Huvudupphovsmän: | , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2010
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033498/ https://ncbi.nlm.nih.gov/pubmed/20863819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.09.015 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|