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Autonomous silencing of the imprinted Cdkn1c gene in stem cells

Parent-of-origin specific expression of imprinted genes relies on the differential DNA methylation of specific genomic regions. Differentially methylated regions (DMRs) acquire DNA methylation either during gametogenesis (primary DMR) or after fertilization when allele-specific expression is establi...

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Bibliographic Details
Main Authors: Wood, Michelle D., Hiura, Hitoshi, Tunster, Simon, Arima, Takahiro, Shin, Jong-Yeon, Higgins, Michael, John, Rosalind M.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033483/
https://ncbi.nlm.nih.gov/pubmed/20372090
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