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Fetal overgrowth in the Cdkn1c mouse model of Beckwith-Wiedemann syndrome
Mutations in the imprinted CDKN1C gene are associated with the childhood developmental disorder Beckwith-Wiedemann syndrome (BWS). Multiple mouse models with deficiency of Cdkn1c recapitulate some aspects of BWS but do not exhibit overgrowth of the newborn, a cardinal feature of patients with BWS. I...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209650/ https://ncbi.nlm.nih.gov/pubmed/21729874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.007328 |
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