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Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex development

The cyclin-dependent kinase inhibitor p57(KIP2) is encoded by the imprinted Cdkn1c locus, exhibits maternal expression, and is essential for cerebral cortex development. How Cdkn1c regulates corticogenesis is however not clear. To this end we employ Mosaic Analysis with Double Markers (MADM) technol...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Laukoter, Susanne, Beattie, Robert, Pauler, Florian M., Amberg, Nicole, Nakayama, Keiichi I., Hippenmeyer, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954230/
https://ncbi.nlm.nih.gov/pubmed/31924768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14077-2
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