Snail Mediates E-Cadherin Repression by the Recruitment of the Sin3A/Histone Deacetylase 1 (HDAC1)/HDAC2 Complex

The transcription factor Snail has been described as a direct repressor of E-cadherin expression during development and carcinogenesis; however, the specific mechanisms involved in this process remain largely unknown. Here we show that mammalian Snail requires histone deacetylase (HDAC) activity to...

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Bibliografiske detaljer
Main Authors: Peinado, Hector, Ballestar, Esteban, Esteller, Manel, Cano, Amparo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC303344/
https://ncbi.nlm.nih.gov/pubmed/14673164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.306-319.2004
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