Snail Mediates E-Cadherin Repression by the Recruitment of the Sin3A/Histone Deacetylase 1 (HDAC1)/HDAC2 Complex

The transcription factor Snail has been described as a direct repressor of E-cadherin expression during development and carcinogenesis; however, the specific mechanisms involved in this process remain largely unknown. Here we show that mammalian Snail requires histone deacetylase (HDAC) activity to...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Peinado, Hector, Ballestar, Esteban, Esteller, Manel, Cano, Amparo
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2004
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303344/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.306-319.2004
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