Carregant...

Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase

Depudecin is a fungal metabolite that reverts the rounded phenotype of NIH 3T3 fibroblasts transformed with v-ras and v-src oncogenes to the flattened phenotype of the nontransformed parental cells. The mechanism of detransformation induced by this agent had not been determined. Here, we demonstrate...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Kwon, Ho Jeong, Owa, Takashi, Hassig, Christian A., Shimada, Junichi, Schreiber, Stuart L.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19839/
https://ncbi.nlm.nih.gov/pubmed/9520369
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!