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EGFR NUCLEAR TRANSLOCATION MODULATES DNA REPAIR FOLLOWING CISPLATIN AND IONIZING RADIATION TREATMENT
EGFR overexpression is associated with resistance to chemotherapy and radiotherapy. EGFR modulates DNA repair after radiation-induced damage through association with the catalytic subunit of DNA protein kinase (DNA-PKcs). We investigated the role of EGFR nuclear import and its association with DNAPK...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033323/ https://ncbi.nlm.nih.gov/pubmed/21266349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2384 |
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