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Stress-specific p38 MAPK activation is sufficient to drive EGFR endocytosis but not its nuclear translocation
EGF receptor (EGFR) endocytosis is induced by stress in a manner dependent on the p38 MAPK family. Ligand and stresses such as X-rays, reportedly promote nuclear trafficking of endocytosed EGFR for regulation of gene transcription and DNA repair. We fail to detect EGFR endocytosis or nuclear transpo...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5558270/ https://ncbi.nlm.nih.gov/pubmed/28646091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.202358 |
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