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Pathways driving the endocytosis of mutant and wild-type EGFR in cancer

EGFR (epidermal growth factor receptor) is activated through changes in expression or mutations in a number of tumors and is a driving force in cancer progression. EGFR is targeted by numerous inhibitors, including chimeric antibodies targeting the extracellular domain and small molecule kinase doma...

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Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: Hampton, Kaia K., Craven, Rolf J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278327/
https://ncbi.nlm.nih.gov/pubmed/25594057
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