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Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1)
Numerous studies indicate that Sirtuin 1 (SIRT1), a mammalian nicotinamide adenine dinucleotide (NAD(+))-dependent histone deacetylase (HDAC), plays a crucial role in p53-mediated stress responses by deacetylating p53. Nevertheless, the acetylation levels of p53 are dramatically increased upon DNA d...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033317/ https://ncbi.nlm.nih.gov/pubmed/21245319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019619108 |
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