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Trinitrophenyl derivatives bind differently from parent adenine nucleotides to Ca(2+)-ATPase in the absence of Ca(2+)
Trinitrophenyl derivatives of adenine nucleotides are widely used for probing ATP-binding sites. Here we describe crystal structures of Ca(2+)-ATPase, a representative P-type ATPase, in the absence of Ca(2+) with bound ATP, trinitrophenyl-ATP, -ADP, and -AMP at better than 2.4-Å resolution, stabiliz...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033254/ https://ncbi.nlm.nih.gov/pubmed/21239683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017659108 |
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