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GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?
Unlike nanocarriers that are intended to release their drug cargo at the site of action, biocompatibile polyamidoamine (PAMAM) conjugates are designed to act at cell surface G protein-coupled receptors (GPCRs) without drug release. These multivalent GPCR Ligand-Dendrimer (GLiDe) conjugates display q...
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Format: | Artigo |
Jezik: | Inglês |
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2010
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033016/ https://ncbi.nlm.nih.gov/pubmed/20961625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2010.09.002 |
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