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GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

Unlike nanocarriers that are intended to release their drug cargo at the site of action, biocompatibile polyamidoamine (PAMAM) conjugates are designed to act at cell surface G protein-coupled receptors (GPCRs) without drug release. These multivalent GPCR Ligand-Dendrimer (GLiDe) conjugates display q...

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Bibliografski detalji
Glavni autor: Jacobson, Kenneth A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033016/
https://ncbi.nlm.nih.gov/pubmed/20961625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2010.09.002
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