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Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel

BACKGROUND: ARHI is a Ras-related imprinted gene that inhibits cancer cell growth and motility. ARHI is downregulated in the majority of breast cancers, and loss of its expression is associated with its progression from ductal carcinoma in situ (DCIS) to invasive disease. In ovarian cancer, re-expre...

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Main Authors: Zou, Chun-Fang, Jia, Luoqi, Jin, Hongyan, Yao, Ming, Zhao, Naiqing, Huan, Jin, Lu, Zhen, Bast, Robert C, Feng, Youji, Yu, Yinhua
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032751/
https://ncbi.nlm.nih.gov/pubmed/21244707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-22
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