ARHI (DIRAS3)-mediated autophagy-associated cell death enhances chemosensitivity to cisplatin in ovarian cancer cell lines and xenografts

Autophagy can sustain or kill tumor cells depending upon the context. The mechanism of autophagy-associated cell death has not been well elucidated and autophagy has enhanced or inhibited sensitivity of cancer cells to cytotoxic chemotherapy in different models. ARHI (DIRAS3), an imprinted tumor sup...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Washington, M N, Suh, G, Orozco, A F, Sutton, M N, Yang, H, Wang, Y, Mao, W, Millward, S, Ornelas, A, Atkinson, N, Liao, W, Bast, R C, Lu, Z
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558501/
https://ncbi.nlm.nih.gov/pubmed/26247722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.208
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