ARHI (DIRAS 3), an imprinted tumor suppressor gene, binds to importins, and blocks nuclear import process of cargo proteins

ARHI (DIRAS3) is an imprinted tumor suppressor gene whose expression is lost in the majority of breast and ovarian cancers. Unlike its homologs Ras and Rap, ARHI functions as a tumor suppressor. Our previous study showed that ARHI can interact with the transcriptional activator Stat3 and inhibit its...

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Autores principales: Huang, Shaoyi, Chang, In Soon, Lin, Wenbo, Ye, Wenduo, Luo, Robert Z., Lu, Zhen, Lu, Yiling, Zhang, Ke, Liao, Warren S-L., Tao, Tao, Bast, Robert C., Chen, Xiaomin, Yu, Yinhua
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974631/
https://ncbi.nlm.nih.gov/pubmed/19435463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20090008
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