The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells

The role of autophagy in oncogenesis remains ambiguous, and mechanisms that induce autophagy and regulate its outcome in human cancers are poorly understood. The maternally imprinted Ras-related tumor suppressor gene aplasia Ras homolog member I (ARHI; also known as DIRAS3) is downregulated in more...

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Détails bibliographiques
Auteurs principaux: Lu, Zhen, Luo, Robert Z., Lu, Yiling, Zhang, Xuhui, Yu, Qinghua, Khare, Shilpi, Kondo, Seiji, Kondo, Yasuko, Yu, Yinhua, Mills, Gordon B., Liao, Warren S.-L., Bast, Robert C.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582930/
https://ncbi.nlm.nih.gov/pubmed/19033662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35512
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