ARHI (DIRAS 3), an imprinted tumor suppressor gene, binds to importins, and blocks nuclear import process of cargo proteins

ARHI (DIRAS3) is an imprinted tumor suppressor gene whose expression is lost in the majority of breast and ovarian cancers. Unlike its homologs Ras and Rap, ARHI functions as a tumor suppressor. Our previous study showed that ARHI can interact with the transcriptional activator Stat3 and inhibit its...

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Detalhes bibliográficos
Main Authors: Huang, Shaoyi, Chang, In Soon, Lin, Wenbo, Ye, Wenduo, Luo, Robert Z., Lu, Zhen, Lu, Yiling, Zhang, Ke, Liao, Warren S-L., Tao, Tao, Bast, Robert C., Chen, Xiaomin, Yu, Yinhua
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974631/
https://ncbi.nlm.nih.gov/pubmed/19435463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20090008
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