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Overexpression of BMI-1 Promotes Cell Growth and Resistance to Cisplatin Treatment in Osteosarcoma

BACKGROUND: BMI-1 is a member of the polycomb group of genes (PcGs), and it has been implicated in the development and progression of several malignancies, but its role in osteosarcoma remains to be elucidated. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, we found that BMI-1 was overexpress...

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Hlavní autoři: Wu, Zhihong, Min, Li, Chen, Dafu, Hao, Dongsheng, Duan, Yuanhui, Qiu, Guixing, Wang, Yipeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032734/
https://ncbi.nlm.nih.gov/pubmed/21311599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014648
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