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BMI1 Is Expressed in Canine Osteosarcoma and Contributes to Cell Growth and Chemotherapy Resistance

BMI1, a stem cell factor and member of the polycomb group of genes, has been shown to contribute to growth and chemoresistance of several human malignancies including primary osteosarcoma (OSA). Naturally occurring OSA in the dog represents a large animal model of human OSA, however the potential ro...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Shahi, Mehdi Hayat, York, Daniel, Gandour-Edwards, Regina, Withers, Sita S., Holt, Roseline, Rebhun, Robert B.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482432/
https://ncbi.nlm.nih.gov/pubmed/26110620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131006
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