BMI1 Is Expressed in Canine Osteosarcoma and Contributes to Cell Growth and Chemotherapy Resistance

BMI1, a stem cell factor and member of the polycomb group of genes, has been shown to contribute to growth and chemoresistance of several human malignancies including primary osteosarcoma (OSA). Naturally occurring OSA in the dog represents a large animal model of human OSA, however the potential ro...

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Bibliographic Details
Published in:PLoS One
Main Authors: Shahi, Mehdi Hayat, York, Daniel, Gandour-Edwards, Regina, Withers, Sita S., Holt, Roseline, Rebhun, Robert B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482432/
https://ncbi.nlm.nih.gov/pubmed/26110620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131006
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