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Overexpression of BMI-1 Promotes Cell Growth and Resistance to Cisplatin Treatment in Osteosarcoma

BACKGROUND: BMI-1 is a member of the polycomb group of genes (PcGs), and it has been implicated in the development and progression of several malignancies, but its role in osteosarcoma remains to be elucidated. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, we found that BMI-1 was overexpress...

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Detalhes bibliográficos
Main Authors: Wu, Zhihong, Min, Li, Chen, Dafu, Hao, Dongsheng, Duan, Yuanhui, Qiu, Guixing, Wang, Yipeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032734/
https://ncbi.nlm.nih.gov/pubmed/21311599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014648
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