miR-33a is up-regulated in chemoresistant osteosarcoma and promotes osteosarcoma cell resistance to cisplatin by down-regulating TWIST

BACKGROUND: miRNAs are involved in osteosarcoma (OS) chemoresistance, and TWIST reportedly enhances cisplatin-induced OS cell apoptosis by inhibiting multiple signaling pathways. In this study, we profiled miRNAs differentially expressed in chemoresistant OS, with a focus to identify miRNAs that reg...

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Hlavní autoři: Zhou, Yong, Huang, Zufa, Wu, Song, Zang, Xiaofang, Liu, Min, Shi, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974149/
https://ncbi.nlm.nih.gov/pubmed/24468065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-33-12
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