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Cellular Uptake of Ribonuclease A Relies on Anionic Glycans
Bovine pancreatic ribonuclease (RNase A) can enter human cells, even though it lacks a cognate cell-surface receptor protein. Here, we report on the biochemical basis for its cellular uptake. Analyses in vitro and in cellulo revealed that RNase A interacts tightly with abundant cell-surface proteogl...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032661/ https://ncbi.nlm.nih.gov/pubmed/21062061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1013485 |
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