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Mechanism of Ribonuclease A Endocytosis: Analogies to Cell-Penetrating Peptides()
Pancreatic-type ribonucleases can exert toxic activity by catalyzing the degradation of cellular RNA. Their ability to enter cells is essential for their cytotoxicity. Here, we determine the mechanism by which bovine pancreatic ribonuclease (RNase A) enters human cells. Inhibiting clathrin-dependent...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242730/ https://ncbi.nlm.nih.gov/pubmed/21827164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2009079 |
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