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Cellular Uptake of Ribonuclease A Relies on Anionic Glycans

Bovine pancreatic ribonuclease (RNase A) can enter human cells, even though it lacks a cognate cell-surface receptor protein. Here, we report on the biochemical basis for its cellular uptake. Analyses in vitro and in cellulo revealed that RNase A interacts tightly with abundant cell-surface proteogl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chao, Tzu-Yuan, Lavis, Luke D., Raines, Ronald T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032661/
https://ncbi.nlm.nih.gov/pubmed/21062061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1013485
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