Cadmium induction of reactive oxygen species activates mTOR pathway, leading to neuronal cell death

Cadmium (Cd), a highly toxic environmental pollutant, induces neurodegenerative diseases. Recently we have demonstrated that Cd induces neuronal apoptosis in part through activation of the mammalian target of rapamycin (mTOR) pathway. However, the underlying mechanism is unknown. Here we show that C...

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Hlavní autoři: Chen, Long, Xu, Baoshan, Liu, Lei, Luo, Yan, Zhou, Hongyu, Chen, Wenxing, Shen, Tao, Han, Xiuzhen, Kontos, Christopher D., Huang, Shile
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032035/
https://ncbi.nlm.nih.gov/pubmed/21195169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.12.032
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