Cadmium induction of reactive oxygen species activates mTOR pathway, leading to neuronal cell death

Cadmium (Cd), a highly toxic environmental pollutant, induces neurodegenerative diseases. Recently we have demonstrated that Cd induces neuronal apoptosis in part through activation of the mammalian target of rapamycin (mTOR) pathway. However, the underlying mechanism is unknown. Here we show that C...

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Huvudupphovsmän: Chen, Long, Xu, Baoshan, Liu, Lei, Luo, Yan, Zhou, Hongyu, Chen, Wenxing, Shen, Tao, Han, Xiuzhen, Kontos, Christopher D., Huang, Shile
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032035/
https://ncbi.nlm.nih.gov/pubmed/21195169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.12.032
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