Calcium Signaling Is Involved in Cadmium-Induced Neuronal Apoptosis via Induction of Reactive Oxygen Species and Activation of MAPK/mTOR Network

Cadmium (Cd), a toxic environmental contaminant, induces oxidative stress, leading to neurodegenerative disorders. Recently we have demonstrated that Cd induces neuronal apoptosis in part by activation of the mitogen-activated protein kineses (MAPK) and mammalian target of rapamycin (mTOR) pathways....

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Detalhes bibliográficos
Main Authors: Xu, Baoshan, Chen, Sujuan, Luo, Yan, Chen, Zi, Liu, Lei, Zhou, Hongyu, Chen, Wenxing, Shen, Tao, Han, Xiuzhen, Chen, Long, Huang, Shile
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081326/
https://ncbi.nlm.nih.gov/pubmed/21544200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019052
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