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Unique Dynamic Properties of DNA Duplexes Containing Interstrand Crosslinks
Bifunctional DNA alkylating agents form a diverse assortment of covalent DNA interstrand crosslinked (ICL) structures that are potent cytotoxins. Since it is implausible that cells could possess distinct DNA repair systems for each individual ICL, it is believed that common structural and dynamic fe...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032004/ https://ncbi.nlm.nih.gov/pubmed/21174443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101813h |
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