Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling

Apoptotic cells are swiftly engulfed by phagocytes and degraded inside phagosomes. Phagosome maturation requires phosphatidylinositol 3-phosphate [PtdIns(3)P], yet how PtdIns(3)P triggers phagosome maturation remains largely unknown. Through a genome-wide PtdIns(3)P effector screen in the nematode C...

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Bibliographic Details
Main Authors: Lu, Nan, Shen, Qian, Mahoney, Timothy R., Liu, Xianghua, Zhou, Zheng
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2011
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031466/
https://ncbi.nlm.nih.gov/pubmed/21148288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.e10-09-0756
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