The Phox Domain of Sorting Nexin 5 Lacks Phosphatidylinositol 3-Phosphate (PtdIns(3)P) Specificity and Preferentially Binds to Phosphatidylinositol 4,5-Bisphosphate (PtdIns(4,5)P(2))

Subcellular retrograde transport of cargo receptors from endosomes to the trans-Golgi network is critically involved in a broad range of physiological and pathological processes and highly regulated by a genetically conserved heteropentameric complex, termed retromer. Among the retromer components i...

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Autores principales: Koharudin, Leonardus M. I., Furey, William, Liu, Hao, Liu, Yong-Jian, Gronenborn, Angela M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749144/
https://ncbi.nlm.nih.gov/pubmed/19553671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.008995
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