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Two PI 3-Kinases and One PI 3-Phosphatase Together Establish the Cyclic Waves of Phagosomal PtdIns(3)P Critical for the Degradation of Apoptotic Cells

Phosphatidylinositol 3-phosphate (PtdIns(3)P) is a signaling molecule important for many membrane trafficking events, including phagosome maturation. The level of PtdIns(3)P on phagosomes oscillates in two waves during phagosome maturation. However, the physiological significance of such oscillation...

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Detalhes bibliográficos
Main Authors: Lu, Nan, Shen, Qian, Mahoney, Timothy R., Neukomm, Lukas J., Wang, Ying, Zhou, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260314/
https://ncbi.nlm.nih.gov/pubmed/22272187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001245
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