Mutation of inhibitory helix-loop-helix protein Id3 causes γδ T-cell lymphoma in mice

Human γδ T-cell lymphoma is a rare clinicopathologic entity with aggressive course and poor prognosis. The etiology and pathogenesis of γδ T-cell lymphoma is unknown. We show here that mice with deficiency in inhibitory helix-loop-helix protein Id3 (Id3(−/−)) developed γδ T-cell lymphoma that resemb...

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Autores principales: Li, Jun, Maruyama, Takashi, Zhang, Pin, Konkel, Joanne E., Hoffman, Victoria, Zamarron, Brian, Chen, WanJun
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2010
Materias:
Lymphoid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031408/
https://ncbi.nlm.nih.gov/pubmed/20852128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-274506
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